It is important that you introduce MK-677 slowly into your daily regime and increase your dosage accordingly. For example, you can start off with 10mg of MK677 a day and up the dosage to 20-25mg a day.
You can safely take up to 25 mg per day of MK-677, preferably taking 12.5 mg at night and 12.5 mg in the morning. As with anything, there is no need to take too much MK-677. Take your time to cycle/stack properly to get the best benefits and avoid side effects.